ddPCR provides absolute concentration of target DNA copies per input sample without the need for running standard curves, making this technique ideal for a variety of applications requiring precise quantification. ddPCR is ideal for detecting genomic alterations such as gene copy number variation, gene and microRNA expression, detection of rare sequences, viral load analysis, and rare mutation detection, such as after CRISPR editing.
Trained users will have keycard access to the lab and will be able to book and use the analytical instruments. For ease of management, molecular biology instruments located in the BNL are also part of the Analytical core. Researchers can also engage BNL staff to perform basic molecular biological experiments such as recombinant protein expression. Cost will be on a project-by-project basis and will include staff man-hours, materials used and instrument recharges.